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Lipid Multi-Layer Gratings for Semi-Synthetic Quorum Sensors

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Tech ID:
11-067
Principal Investigator:
Dr. Lenhert
Licensing Manager:
Patents:
Description:

The present invention provides a device comprising: a substrate, and a quorum sensor array on the substrate. The quorum sensor array comprises quorum sensors releasing signal molecules in response to one or more environmental signals being sense by the quorum sensors to thereby amplify the one or more environmental signals by causing a signal chain reaction in neighboring quorum sensors of the quorum sensor array, and wherein each of the quorum sensors comprises a lipid multi-layer structure.

The present invention provides a method comprising the following steps: (a) detecting with a camera one or more light intensities of light scattered by one or more iridescent microstructures of a sample, and (b) determining a height of each of the one or more iridescent microstructures of the sample based on one or more light intensities detected in step (a) and a calibration profile for the camera, wherein the calibration profile is based on light intensities detected by the camera for light scattered one or more patterned arrays of standard iridescent microstructures of a calibration standard, and wherein each of the patterned arrays of iridescent microstructures comprises iridescent microstructures having the same shape and two or more different heights.